Antimicrobial Activity of Five Medicinal Plants on Candida Albicans

Masomi, Fatemeh; Hassanshahian, Mehdi

doi:10.29252/arakmu.10.6.39

Write your message

ارسال به ایمیل

Volume 10, Issue 6 (November-December 2016) IJT 2016, 10(6): 39-43 | Back to browse issues page

‎ 10.29252/arakmu.10.6.39

Mendeley

Zotero

RefWorks

Masomi F, Hassanshahian M. Antimicrobial Activity of Five Medicinal Plants on Candida Albicans. IJT 2016; 10 (6) :39-43
URL: http://ijt.arakmu.ac.ir/article-1-513-en.html

Antimicrobial Activity of Five Medicinal Plants on Candida Albicans

Fatemeh Masomi¹

, Mehdi Hassanshahian ^*

1- Department of Biology, Shahid Bahonar University of Kerman, Kerman, Iran.
2- Department of Biology, Shahid Bahonar University of Kerman, Kerman, Iran. , mshahi@uk.ac.ir

Abstract: (4900 Views)

Background: In recent years, drug resistance to human pathogenic fungi has been increased. Medicinal plants are one way to overcome antibiotic resistance. The aim of this study was to evaluate the antifungal and inhibitory activity of five medicinal plants on the growth of Candida albicans.

Methods: This study was done in the Microbiology Lab of Shahid Bahonar University of Kerman, Iran in 2015. Five medicinal plants include: Trachyspermum ammi (seed), Teucrium polium (leaf), Piper nigrum (seed), Pistachia vera (skin), Camelia sinensis (leaf) were collected. Collected plant materials were extracted by ethanol and methanol solvent with maceration method. Antifungal activity of the ethanolic and methanolic extracts was evaluated by paper disc diffusion and agar well diffusion methods. Besides, MIC and MBC of each extract was determined.

Results: All plant extracts had sufficient inhibitory effect against C. albicans but the extracts of P. vera had the best inhibitory effect on C. albicans (ZOI: 40 mm). The lowest antifungal effect between these five plants related to Piper nigrum (ZOI: 13 mm). Besides, the P. vera extracts had the best MIC and MBC values (6.25 and 12.5 mg/ml).

Conclusion: This study strongly evidence the maximum antimicrobial activity of medicinal plants against C. albicans that this inhibitory effect varies with the different solvent-extract form. A more comprehensive study need to identify the effective compounds that have these antifungal properties.

Keywords: Antibiotic, Antifungal Activity, Extracts, Medicinal Plants, Inhibitory Effect

Full-Text [PDF 124 kb] (2913 Downloads)

Type of Study: Research | Subject: Special

References

1. Harbottle H, Thakur S, Zhao S, White D. Genetics of antimicrobial resistance. Animal biotechnology. 2006;17(2):111-24. [DOI:10.1080/10495390600957092]

2. Kao AS, Brandt ME, Pruitt WR, Conn LA, Perkins BA, Stephens DS, et al. The epidemiology of candidemia in two United States cities: results of a population-based active surveillance. Clin Infect Dis 1999;29(5):1164-70. [DOI:10.1086/313450]

3. Ficker CE, Smith ML, Susiarti S, Leaman DJ, Irawati C, Arnason JT. Inhibition of human pathogenic fungi by members of Zingiberaceae used by the Kenyah (Indonesian Borneo). J Ethnopharmacol 2003;85(2):289-93. [DOI:10.1016/S0378-8741(03)00009-6]

4. Atai Z, Atapour M, Mohseni M. Inhibitory effect of ginger extract on Candida albicans. Amer J Appl Scien 2009;6(6):1067-9. [DOI:10.3844/ajassp.2009.1067.1069]

5. Ahmad I, Beg AZ. Antimicrobial and phytochemical studies on 45 Indian medicinal plants against multi-drug resistant human pathogens. J Ethnopharmacol 2001;74(2):113-23. [DOI:10.1016/S0378-8741(00)00335-4]

6. Duarte MCT, Figueira GM, Sartoratto A, Rehder VLG, Delarmelina C. Anti-Candida activity of Brazilian medicinal plants. J Ethnopharmacol 2005;97(2):305-11. [DOI:10.1016/j.jep.2004.11.016]

7. Zarshenas MM, Moein M, Samani SM, Petramfar P. An overview on ajwain (Trachyspermum ammi) pharmacological effects; modern and traditional. J Natur Rem 2013;14(1):98-105.

8. Bonnier G. La grandeflore en couleur. Librairie Belin: Paris.1990.p.943-8.

9. Coste H, Flahault C. Flore descriptive et illustrée de la France, de la Corse, et des contrées limitrophes: P. Klincksieck; 1903.p.139-40.

10. Chang F-R, Hwang T-L, Yang Y-L, Li C-E, Wu C-C, Issa HH, et al. Anti-inflammatory and cytotoxic diterpenes from formosan Polyalthia longifolia var. pendula. Planta medica 2006;72(14):1344-7. [DOI:10.1055/s-2006-951691]

11. Rani SS, Saxena N. Udaysree: Antimicrobial Activity of Black Pepper (Piper nigrum L.). Glob J Pharmacol.2013;5(1):87-90.

12. Dogan Y, Baslar S, Ayden H, Mert HH. A study of the soil-plant interactions of Pistacia lentiscus L. distributed in the western Anatolian part of Turkey. Acta Bot Croat 2003;62(2):73-88.

13. Ghalem B, Mohamed B. Antimicrobial activity evaluation of the oleoresin oil of Pistacia vera L. Afr J Pharma Pharmacolo 2009;3(3):092-6.

14. Gupta D, Bhaskar D, Gupta R, Karim B, Jain A, Dalai D. Green tea: A review on its natural anti-oxidant therapy and cariostatic benefits. Biol Scien Pharma Res 2014;2(1):008-12.

15. Cabrera C, Artacho R, Giménez R. Beneficial effects of green tea—a review. J Am College Nut 2006;25(2):79-99. [DOI:10.1080/07315724.2006.10719518]

16. Reygaert WC. The antimicrobial possibilities of green tea. Front Microbiol 2014;5:434. [DOI:10.3389/fmicb.2014.00434]

17. Keller AC, Weir TL, Broeckling CD, Ryan EP. Antibacterial activity and phytochemical profile of fermented Camellia sinensis (fuzhuan tea). Food Res Inter 2013;53(2):945-9. [DOI:10.1016/j.foodres.2013.04.023]

18. Moein MR, Zomorodian K, Pakshir K, Yavari F, Motamedi M, Zarshenas MM. Trachyspermum ammi (L.) Sprague Chemical Composition of Essential Oil and Antimicrobial Activities of Respective Fractions. J Evid Med 2015;20(1):50-6.

19. Pirbalouti AG, Bahmani M, Avijgan M. Anti-Candida activity of some of the Iranian medicinal plants. Elect J Biol 2009;5:85-8.

20. Paula CR, Krebs VL, Auler ME, Ruiz LS, Matsumoto FE, Silva EH, et al. Nosocomial infection in newborns by Pichia anomala in a Brazilian intensive care unit. Med Mycol 2006;44(5):479-84. [DOI:10.1080/13693780600561809]

Send email to the article author

Rights and permissions
	This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Designed & Developed by : Yektaweb