Iranian Journal of Toxicology
مجله سم شناسی و مسمومیتهای ایران
IJT
Medical Sciences
http://ijt.arakmu.ac.ir
1
admin
2008-2967
2251-9459
8
10.61186/ijt
14
8888
13
en
jalali
1396
5
1
gregorian
2017
8
1
11
5
online
1
fulltext
en
Estradiol Affects Prolactin Producing Cells and Calcium levels in a Teleost, Heteropneustesfossilis, Kept in Different Calcium Concentrations
عمومى
General
پژوهشي
Research
<strong>Background: </strong>This study investigated the effects of estradiol on plasma calcium and prolactin cells of <em>Heteropneustes fossilis</em> kept in calcium-deficient and normal freshwater<em>. </em><br>
<strong>Methods: </strong>Fish were deprived of food and divided into groups A-D. Group A and B were kept in artificial freshwater with normal electrolytes. Group C and D were maintained in calcium-deficient freshwater. Vehicle was administered to groups A and C. Groups B and D were injected with estradiol. Plasma calcium levels and prolactin cells were studied after 1, 3, 5, 10 and 15 days.<br>
<strong>Results: </strong>Normal-calcium freshwater: In group A calcium levels remained unaffected. In group B, estradiol provoked hypercalcemia from day 3 to 10 although calcium decreased after day 15. Prolactin cells in group B became degranulated after 10day. Nuclear volume increased from day 10 onwards.<br>
Calcium-deficient freshwater: Calcium levels in group C decreased from day 1 to 3 thereafter increased from day 5 to 15. Plasma calcium of group D increased from day 3 to 15. In group C prolactin cells exhibited hyperactivity on day 3 and degranulation on day 5. Nuclear volume increased from day 5 onwards. On day 10 and 15 certain cells became degenerated. In group D degranulation of prolactin cells began on day 3 which proceeded to complete degranulation on day 10. Nuclear volume increased from day 5 onwards.<br>
<strong>Conclusions:</strong> Estradiol enhanced prolactin production and increased blood calcium in food-deprived fishes kept in calcium-deficient medium suggesting that calcium needed for elevation of blood calcium was derived from internal sources.
Estradiol, Prolactin Cells, Plasma Calcium, Fish
Calcium, Catfishes, Estradiol, Fishes, Prolactin
45
51
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-74-4&slc_lang=en&sid=1
Susmita
Srivastav
10031947532846006485
10031947532846006485
No
Department of Zoology, Shiv Harsh Kisan P. G. College, Basti-272001, India.
Diwakar
Mishra
10031947532846006486
10031947532846006486
No
Department of Zoology, Government Girls’ P. G. College, Ghazipur-233001, India.
Sunil Kumar
Srivastav
10031947532846006487
10031947532846006487
No
Department of Zoology, D. D. U. Gorakhpur University, Gorakhpur-273009, India.
Nobuo
Suzuki
10031947532846006488
10031947532846006488
No
PhD. Noto Marine Laboratory, Institute of Nature and Environmental Technology, Kanazawa University, Ogi, Noto-cho, Ishikawa, Japan.
Ajai Kumar
Srivastav
ajaiksrivastav@hotmail.com
10031947532846006489
10031947532846006489
Yes
Department of Zoology, D. D. U. Gorakhpur University, Gorakhpur-273009, India.