Iranian Journal of Toxicology
مجله سم شناسی و مسمومیتهای ایران
IJT
Medical Sciences
http://ijt.arakmu.ac.ir
1
admin
2008-2967
2251-9459
8
10.61186/ijt
14
8888
13
en
jalali
1396
11
1
gregorian
2018
2
1
12
2
online
1
fulltext
en
Respiratory Apnea in Patients with Acute Poisoning by Tramadol (Two Years Study)
تخصصي
Special
پژوهشي
Research
<strong>Background</strong><strong>:</strong> Tramadol is an analgesic drug being abused today a lot. Excessive ingestion will lead to hazardous complications such as convulsion and occasionally respiratory apnea. The aim of this study based on frequency respiratory apnea in patients with acute tramadol poisoning hospitalized in Farshchian Hospital of Hamadan, Iran from Jan 2014 to Dec 2015.<br>
<strong>Methods:</strong> All patients with tramadol poisoning who hospitalized and treated at poisoning ward were enrolled into the study. Their demographic data including age, gender, drug ingestion dose, and respiratory apnea leading to taking naloxone or intubation collected and analyzed statistically by SPSS software.<br>
<strong>Results:</strong> Overall, 350 patients aged between 14 to 68 yr old were investigated. About 75% of them were male and among them, 81.14% had deliberate self-poisoning. 4.86% developed apnea whose average tramadol consumption was 4158.83 mg. In patients who had not apnea, the average tramadol consumption was 122.38 mg, that was statistically significant difference (<em>P</em><0.001).<br>
<strong>Conclusion:</strong> Although apnea development frequency in patients with excessive tramadol ingestion is rare, it is significant as a potentially life-threatening risk, occasionally ignored.
Apnea, Iran, Poisoning, Tramadol
33
35
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-94-2&slc_lang=en&sid=1
Seyed Kazem
Taheri
10031947532846007268
10031947532846007268
No
Department of Forensic Medicine and Toxicology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Gholamali
Dorooshi
10031947532846007269
10031947532846007269
No
Department of Forensic Medicine and Toxicology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Saeed
Afzali
afzali691@yahoo.com
10031947532846007270
10031947532846007270
Yes
Department of Forensic Medicine and Toxicology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.