Iranian Journal of Toxicology
مجله سم شناسی و مسمومیتهای ایران
IJT
Medical Sciences
http://ijt.arakmu.ac.ir
1
admin
2008-2967
2251-9459
8
10.61186/ijt
14
8888
13
en
jalali
1396
11
1
gregorian
2018
2
1
12
2
online
1
fulltext
en
In Vitro Binding Potentials of Bentonite, Yeast Cell Wall and Lactic Acid Bacteria for Aflatoxin B1 and Ochratoxin A
عمومى
General
پژوهشي
Research
<strong>Background:</strong> This study intended to assess individual and combined adsorption potentials of three adsorbents (processed bentonite as an inorganic adsorbent, and cell walls of <em>Saccharomyces cerevisiae</em> and of the GG strain of <em>Lactobacillus rhamnosus</em> as organic adsorbents) for aflatoxin B<sub>1</sub> and ochratoxin A under in vitro conditions.<br>
<strong>Methods:</strong> This study was conducted in Ferdowsi University of Mashhad, Mashhad, Iran in 2106. A pre-test with four treatments of bacteria and yeast (live or dead) with five replications was designed and conducted to study the effects of these biotic and abiotic organic adsorbents on toxin adsorption efficiency. The experiment in the main study had seven treatments including two toxins (2 ppm) and three adsorbents with five replications using the completely randomized design. Toxin quantities were measured by an HPLC instrument.<br>
<strong>Results:</strong> The various types of dead organic adsorbents were more capable of adsorbing toxins compared to the live ones. The processed bentonite was considerably more efficient in adsorbing aflatoxin B<sub>1</sub> (93.51) compared to the other treatment groups (<em>P</em><0.05). No significant differences were observed between the effects of yeast and bacterial cell walls in adsorbing aflatoxin B<sub>1</sub>. However, the bacterial cell walls (61.71) had higher adsorption efficiencies in adsorbing ochratoxin A than the processed bentonite and yeast cell walls (<em>P</em><0.05).<br>
<strong>Conclusion:</strong> Processed bentonite (or montmorillonite) and bacterial cell walls are able to adsorb considerable quantities of aflatoxin B<sub>1</sub>and ochratoxin A, and can be used in multiple mycotoxin contaminations as an effective strategy for preventing or reducing the harmful effects of these toxins.
Adsorbents, Bentonite, Detoxification, Lactobacillus, Mycotoxin, Yeast Cell Wall
7
13
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-486-1&slc_lang=en&sid=1
Damoon
Ghofrani Tabari
10031947532846007261
10031947532846007261
No
Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran.
Hassan
Kermanshahi
hassbird@yahoo.com
10031947532846007262
10031947532846007262
Yes
Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran.
Abolghasem
Golian
10031947532846007263
10031947532846007263
No
Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran.
Reza
Majidzadeh Heravi
10031947532846007264
10031947532846007264
No
Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran.