en تخصصي Special پژوهشي Research <div style="text-align: justify;"><span style="font-size:12px;"><span style="background:white"><span new="" roman="" style="font-family:" times=""><b>Background: </b>Investigation into environmental chemicals and their impact on human health is a topic of great interest. It is essential to understand the relationship between the quantity of chemical substances involved and the prevalence of particular diseases. Bisphenol-A (BPA) is a disrupting agent to human endocrine health. Human exposure to BPA is on the rise due to the widespread use of this agent, particularly in manufacturing industries. This study aimed to investigate the concentrations of BPA in the Iraqi population. </span></span><br> <span style="background:white"><span new="" roman="" style="font-family:" times=""><b>Methods: </b>This study aimed to determine the amount of BPA in the urine samples of 100 adults residing in the three cities of Diyalah, Kirkuk,<i> </i>and Solaymania in northeastern Iraq. After the subjects&rsquo; urine samples were collected, the overall, free, and conjugated BPA contents of the samples were measured using high-performance liquid chromatography and mass spectroscopy (HPLC/MS). The data were adjusted based on the precalculated creatinine levels in the subjects. </span></span><br> <span style="background:white"><span new="" roman="" style="font-family:" times=""><b>Results: </b>Urine samples were collected from 100 individuals residing in three different cities in Iraq, comprising 47 men and 53 women. <span style="background:white">The concentrations of BPA in all participants&rsquo; urine samples ranged from greater than the limit of quantification to 80.24 &micro;g/g creatinine, with a calculated geometric mean of 4.17 &micro;g/g creatinine.</span></span></span></span><br> <span style="font-size:11pt"><span style="background:white"><span new="" roman="" style="font-family:" times=""><span style="font-size:12px;"><b><span style="letter-spacing:-.1pt">Conclusion: </span></b></span><span style="font-size:8.0pt"><span style="font-size:12px;">The findings of this preliminary study indicated that the Iraqi population&rsquo;s level of BPA exposure falls within an acceptable range. To provide a more accurate estimate of BPA exposure nationwide, further investigations on larger sample sizes are required across a wider range of age and gender distributions.</span> </span></span></span></span></div> BPA-conjugate, Endocrine disruptor, Iraqi population, Urinary Bisphenol-A 106 112 http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-1178-1&slc_lang=en&sid=1 Dastan Salim Hassan Muhammed dastansalim@yahoo.com 100319475328460016614 100319475328460016614 Yes Department of Toxicology, Faculty of Pharmacy, Near East University, Nicosia, North Cyprus Sahan Saygi sahan.saygi@neu.edu.tr 100319475328460016615 100319475328460016615 No Professor, Department of Toxicology, Faculty of Pharmacy, Near East University, Nicosia, North Cyprus