en عمومى General پژوهشي Research <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Tahoma;"><b><span style="color:#2d73b4">Background: </span></b>The present study aimed to assess the oxidative and toxic effects of a 50 Hz magnetic field (MF) and aluminum chloride&nbsp;(AlCl3), as well as the protective effect of Myrtus communis extract, on the plasma and hemoglobin of rats.<br> <b><span style="color:#2d73b4">Methods: </span></b>For the purpose of the study, 50 Hz and 1 mT alternating MFs were administered to Wistar rats. The regime was applied for one month with 2 h each day. The rats were subjected to&nbsp;daily intraperitoneal injections&nbsp;of 8 mg/kg AlCl3; moreover, 2 h before the injections, 1.5 mg/kg extract of Myrtus communis was administered in the form of gavage. After experiments, blood samples were taken from the rats, and oxyhemoglobin, methemoglobin, and hemichrome levels were measured in the samples. In addition, Ferric Reducing Ability of <span style="color:black">Plasma (FRAP) and <em><span style="background:white">Malondialdehyde (</span></em>MDA) tests </span>were also performed.<br> <b><span style="color:#2d73b4">Results: </span></b>Exposing the rats to separate alternating MF and AlCl₃ resulted in a marked decrease in FRAP (P<0.01) and an increase in MDA (P<0.01). Furthermore, simultaneous exposure of rats to alternating MF and AlCl3 enhanced the above oxidative effects synergically (P<0.01). In these effects, the use of the extract of Myrtus communis significantly decreased the adverse oxidative effects (P<0.01). </span></span><br> <span style="font-size:11pt"><span new="" roman="" style="font-family:" times=""><span style="font-size:12px;"><span style="font-family:Tahoma;"><b><span style="color:#2d73b4"><span style="letter-spacing:-.1pt">Conclusion: </span></span></b></span></span><span style="font-size:8.0pt"><span style="font-size:12px;"><span style="font-family:Tahoma;">As evidenced by the results of this study, alternating MF and AlCl₃ exert an oxidant effect separately; moreover, their simultaneous use brings about a synergic effect and results in adverse biological impacts. Furthermore, Myrtus communis extract has a protective effect against these oxidant effects.</span></span> </span></span></span><br> &nbsp;</div> AlCl3, Alternating magnetic field, Antioxidative effects, Myrtus communis 160 166 http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-875-2&slc_lang=en&sid=1 Mohamadreza Bayatiani mr_kbi@yahoo.com 100319475328460018853 100319475328460018853 No Arak University of Medical Sciences Hadi Ansarihadipour hadyansary@yahoo.com 100319475328460018854 100319475328460018854 No Arak University of Medical Sciences Fatemeh Seif sahar_s59@yahoo.com 100319475328460018855 100319475328460018855 Yes Arak University of Medical Sciences Samira Sadelaji Sadelaji.s@yahoo.com 100319475328460018856 100319475328460018856 No Arak University of Medical Sciences Ghasem Habibi ghasem.habibi@gmail.com 100319475328460018857 100319475328460018857 No Arak University of Medical Sciences