en Evaluation of Residues of D.D.T and D.D.A in Fish Collected from Caspian Sea, Iran تخصصي Special پژوهشي Research <b>Background: </b>Pesticides are essential in modern agricultural practices but due to their biocide activity and potential risk to the consumer, the control of pesticide residues in foods is a growing source of concern for the general population. Extensive application of such agents as organochlorine pesticides in farmlands and contemporary agricultural industries has led to undesired environmental contamination and human health hazards. Thus, this study attempted to evaluate and analyze the residual values of the organochlorine insecticide D.D.T and its metabolite D.D.A in the four species of most consumed fish collected from the Caspian Sea. <br> <b>Methods:</b> In this investigation, concentrations of residual values of D.D.T and D.D.A were quantitatively determined in the 4 species of fish sampled from 4 major fishing centers (Chalous and Babolsar cities and Khazar Abad and Miankaleh regions) in Mazandaran province, Iran, using gas chromatography electron-capture detection (GC–ECD) in 2008. <br><b>Results: </b>The results showed that the highest values of D.D.T were in Mugil auratns (0.033±0.008 mg/kg) and Rutilus frisikutum (0.031±0.007 mg/kg) fishes collected from Babolsar sampling center. <br><b>Conclusion: </b>Concentrations of D.D.T and D.D.A in the fish were found to be less than the standard permissible intake. Caspian Sea, D.D.A, D.D.T, Fish, Organochlorine Pesticide. Caspian Sea, D.D.A, D.D.T, Fish, Organochlorine Pesticide. 704 708 http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-2-103&slc_lang=en&sid=1 Mohammad Shokrzadeh lamuki محمد شکرزاده لموکی m_ali_shokrzadeh@yahoo.com 10031947532846002479 10031947532846002479 Yes Department of Toxicology-Pharmacology, Faculty of Pharmacy, Pharmaceutical Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Department of Toxicology-Pharmacology, Faculty of Pharmacy, Pharmaceutical Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Seyed Soheil Saeedi Saravi سید سهیل سعیدی ساروی 10031947532846002480 10031947532846002480 No Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Nasrin Otadi نسرین اوتادی 10031947532846002481 10031947532846002481 No Science and Research Branch ,Islamic Azad University, Tehran, Iran. Science and Research Branch ,Islamic Azad University, Tehran, Iran.