en Toxicological Investigation of Acute Carbon Monoxide Poisoning in ‎Four Occupants of a Fuming Sport Utility Vehicle ‎ تخصصي Special پژوهشي Research <b>Background:</b> This toxicological investigation involves a report on the death of four ‎occupants of a sport utility vehicle on one of the major busy Federal roads of Nigeria ‎where they were held for up to three hours in a traffic jam while the car was steaming.‎ <br><b>Methods: </b>Autopsy was executed using the standard procedure and toxicological ‎analysis was done using simple spectrophotometric method to establish the level of ‎carboxyhaemoglobin (HbCO) in peripheral blood in the four occupants. <br> ‎ <b>Results: </b>The autopsy report indicated generalized cyanosis, sub-conjuctival ‎hemorrhages, marked laryngo-trachea edema with severe hyperemia with frothy fluid ‎discharges characteristic of carbon monoxide poisoning. Toxicological report of the level ‎of HbCO in part per million (ppm) in the peripheral blood of the four occupants was A= ‎‎650 ppm B= 500 ppm C= 480 ppm, and D= 495 ppm against the maximum permissible ‎level of 50 ppm.‎ <b><br>Conclusion: </b>The sudden death of the four occupants was due to excessive inhalation ‎of the carbon monoxide gas from the exhaust fumes leaking into the cabin of the car. ‎The poor road network, numerous potholes, and traffic jam in most of roads in Nigeria ‎could have exacerbated a leaky exhaust of the smoky second hand SUV car leading to ‎the acute carbon monoxide poisoning. ‎ Acute Poisoning, Autopsy, Carbon Monoxide, Toxicological Studies.‎ Acute Poisoning, Autopsy, Carbon Monoxide, Toxicological Studies.‎ 973 976 http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-2-143&slc_lang=en&sid=1 Martin Nnoli Martin Nnoli mnnoli@yahoo.com 10031947532846002274 10031947532846002274 Yes Department of Pathology and Forensic Medicine, University of Calabar, Cross-River State, Nigeria.‎ Department of Pathology and Forensic Medicine, University of Calabar, Cross-River State, Nigeria.‎ Nwidu Lucky Lebgbosi Nwidu Lucky Lebgbosi 10031947532846002275 10031947532846002275 No Department of Pharmacology/Toxicology, Wilberforce Island, Bayelsa State, Nigeria. ‎ Department of Pharmacology/Toxicology, Wilberforce Island, Bayelsa State, Nigeria. ‎ ‎ Innocent Ijezie Chukwuonye ‎ Innocent Ijezie Chukwuonye 10031947532846002276 10031947532846002276 No Department of Internal Medicine/Hematology, Federal Medical Center Umuahia, Abia State, Nigeria.‎ Department of Internal Medicine/Hematology, Federal Medical Center Umuahia, Abia State, Nigeria.‎ Collins Ogbonna Nwabuko Collins Ogbonna Nwabuko 10031947532846002277 10031947532846002277 No Department of Hematology, Federal Medical Center, Umuahia, Abia State, Nigeria.‎ Department of Hematology, Federal Medical Center, Umuahia, Abia State, Nigeria.‎