Iranian Journal of Toxicology
مجله سم شناسی و مسمومیتهای ایران
IJT
Medical Sciences
http://ijt.arakmu.ac.ir
1
admin
2008-2967
2251-9459
8
10.61186/ijt
14
8888
13
en
jalali
1394
11
1
gregorian
2016
2
1
10
2
online
1
fulltext
en
Effects of Naphthalene on Plasma Cortisol and Thyroid Levels in Immature and Mature Female Klunzingeri Mulet, Liza klunzingeri
Effects of Naphthalene on Plasma Cortisol and Thyroid Levels in Immature and Mature Female Klunzingeri Mulet, Liza klunzingeri
تخصصي
Special
پژوهشي
Research
<p dir="ltr"><strong>Background:</strong> Polycyclic aromatic hydrocarbons (PAHs) such as naphthalene (NAP) are organic pollutants that have spread widely in littoral marine ecosystems. We aimed to study the effect of acute and prolonged exposure to naphthalene (NAP) on plasma cortisol and thyroid levels in mature and immature <em>Liza klunzingeri</em> mulet.</p>
<p dir="ltr"><strong>Methods:</strong> In acute stress experiment, the treatment group received 2μl g<sup>-1</sup> sunflower oil containing NAP (50 mg kg<sup>-1</sup>) intraperitoneally and the controls were injected with sunflower oil alone (2μl g<sup>-1</sup>). Blood samples were obtained from both groups after 3 h. In prolonged stress experiment, 10 μl g<sup>-1</sup> of coconut oil containing NAP (50mg kg<sup>-1</sup>) was implanted and blood samples were obtained 72 h after injection.</p>
<p dir="ltr"><strong>Results:</strong> Both the acute and prolonged exposure induced significant increase in cortisol and a significant decrease (<em>P</em><0.05) in thyroid hormone T4 levels. Thyroid T3 hormone levels only decreased significantly (<em>P</em><0.05) after prolonged exposure. Acute exposure resulted in significant decrease (<em>P</em><0.05) in T3/T4 ratio only in immature fish. On the other hand, prolonged stress increased T3/T4 ratio in immature fish.</p>
<p dir="ltr"><strong>Conclusion:</strong> Changes in the plasma levels of these hormones indicate low physiological capacity and survival potential of fish in waters polluted with naphthalene.</p>
Hydrocortisone, Naphthalenes, Polycyclic Aromatic Hydrocarbons, Thyroid Hormones, Triiodothyronine
45
49
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-312-1&slc_lang=en&sid=1
Zahra
Yarahmadi
زهرا
یاراحمدی
100319475328460011169
100319475328460011169
No
Department of Marine Biology, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Department of Marine Biology, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Abdol Ali
Movahedinia
عبدالعلی
موحدی نیا
100319475328460011170
100319475328460011170
No
Department of Marine Biology, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Department of Marine Biology, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Sara
Rastgar
سارا
رستگار
100319475328460011171
100319475328460011171
No
Department of Marine Biology, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Department of Marine Biology, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Rashid
Alijani Ardeshir
رشید
علیجانی اردشیر
r.alijani@kmsu.ac.ir
100319475328460011172
100319475328460011172
Yes
Department of Marine Biology, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
Department of Marine Biology, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.