en عمومى General پژوهشي Research <strong>Background:</strong> Flubendiamide, comparatively a new pesticide designed to eradicate lepidopteran insect pests is known to have low risk to birds, mammals, fish, algae, honey bees, non-target arthropods, earthworms, soil macro- and micro-organisms, non-target plants as well as sewage treatment organisms; however, the risk assessment for aquatic invertebrates from metabolite could not be finalized with available data.<br> <strong>Methods:</strong> Different concentrations of flubendiamide (TATA TAKUMI^&reg;, Rallis, India) were introduced to larvae, pupae, and adult flies. A wide range of comparatively higher concentrations was selected for acute LC₅₀ than chronic LC₅₀due to their exposure duration. Furthermore, relatively lower concentrations were introduced to larvae for assessment of emergence.<br> <strong>Results:</strong> At chronic exposure, the effect-concentration relationship exhibited a linear response when adult emergence was considered in <em>Drosophila melanogaster</em>. When acute LC₅₀ of flubendiamide in 3^rd instar larvae was compared with the chronic LC₅₀ then it was seen to be approximately 21 fold higher whereas chronic LC₅₀ for adult flies was nearly 19 times less than the adult acute LC₅₀. Similarly, adult emergence was seen to lower by 91.95% at 1500 &micro;g/mL concentration. The chronic LC₅₀ of the flubendiamide in <em>Drosophila</em> was approximately 170303 times more than the reported No Observed Effect Concentration (NOEC).<br> <strong>Conclusion:</strong> Hence, the chemical, flubendiamide can induce its effects at very low concentration, far below the lethal ones. Thus, the study is of relevance for the non-target insects as well as the insect dependent organisms. Drosophila Melanogaster, Emergence, Flubendiamide, LC50 45 50 http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-477-1&slc_lang=en&sid=1 Saurabh Sarkar 100319475328460011240 100319475328460011240 No Department of Zoology, The University of Burdwan, Burdwan, India. Prem Rajak 100319475328460011241 100319475328460011241 No Department of Zoology, ABN Seal College, Cooch Behar, India. Sumedha Roy roysumedha@gmail.com 100319475328460011242 100319475328460011242 Yes Department of Zoology, the University of Burdwan, Burdwan, India.