Iranian Journal of Toxicology
مجله سم شناسی و مسمومیتهای ایران
IJT
Medical Sciences
http://ijt.arakmu.ac.ir
1
admin
2008-2967
2251-9459
8
10.61186/ijt
14
8888
13
en
jalali
1386
6
1
gregorian
2007
9
1
1
3
online
1
fulltext
en
Comparative evaluation of Wide QRS Interval and R Changes in Avr Lead in Predicting Severe Complications of Tricyclic Antidepressant Poisoning
Comparative evaluation of Wide QRS Interval and R Changes in Avr Lead in Predicting Severe Complications of Tricyclic Antidepressant Poisoning
عمومى
General
پژوهشي
Research
<span style="font-weight: bold">Background:</span> Tricyclic antidepressants (TCAS) Poisoning is the most common poisoning in the Poisoning Emergency Department of Noor Hospital, Isfahan, Iran. The objective of this study was to compare QRS interval duration with RaVR³3mm and R/SaVR³ 0.7 in predicting: serious complications of acute TCA toxicity.
<br><span style="font-weight: bold">Methods and Materials:</span> This study was descriptive – analytic and prospective cohort. TCA poisoned patients (155 cases) were evaluated in the Emergency Department of Noor Hospital, Isfahan. On admission time, ECG and ABGs were done. Data were analyzed by SPSS Software, using t – students and chi- square tests. <br>
<span style="font-weight: bold">Results:</span> The ECG results showed that frequency of RaVR³3mm , R/SaVR³ 0.7 , QRS³0.1(s), QT> 0.48(s) , Right axis deviation and arrhythmia were 5.2% ,12.9% , 37.4% , 8.38% , 12.4% and 4.5 % respectively. There was a significant relationship between widening of QRS with arrhythmia RaVR³3mm with tachycardia and delirium and R/SaVR³ 0.7 with delirium, seizure, tachycardia, hypotension and arrhythmia. QRS interval duration (61.5% -85.7%) was found to be a more sensitive indicator of toxicity than the R/SaVR ³ 0.7 (27.1% -30.7%) and RaVR>3mm (7.6% -14.2%). The positive prodective values (PPV) of ECG parameters for TCA toxicity for R/SaVR ³0.7 (20%) was more than RaVR³3mm (12.5%) and widening QRS (10.3%).
<br><span style="font-weight: bold">Conclusion: </span>Specific ECG parameters such as R/SaVR, QRS interval duration and height of the R wave in lead aVR can be useful parameters in assessing and predicting cardiac and CNS complication of TCA toxicity.
Tricyclic Antidepressants, Widening QRS Toxicity, RaVR Modifications.
Tricyclic Antidepressants, Widening QRS Toxicity, RaVR Modifications.
2
2
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-2-60&slc_lang=en&sid=1
Farzad
Gheshlaghi
فرزاد
قشلاقی
Gheshlaghi@med.mui.ac.ir
10031947532846003458
10031947532846003458
Yes
Department of Anesthesiology, School of medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Department of Anesthesiology, School of medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Nastaran
Ezadi Mood
نسترن
ایزدی مود
10031947532846003459
10031947532846003459
No
Department of Anesthesiology, School of medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Department of Anesthesiology, School of medicine, Isfahan University of Medical Sciences, Isfahan, Iran