Iranian Journal of Toxicology
مجله سم شناسی و مسمومیتهای ایران
IJT
Medical Sciences
http://ijt.arakmu.ac.ir
1
admin
2008-2967
2251-9459
8
10.61186/ijt
14
8888
13
en
jalali
1400
4
1
gregorian
2021
7
1
15
3
online
1
fulltext
en
بررسی وضعیت مصرف متادون بر اساس آزمایشات سمشناسی در فوتشدگان به علت سوء مصرف مواد مخدر در سالهای 96-1394
Evaluation of Methadone Consumption Rate Based on Post-mortem Toxicology Examinations in Cases of Drug-related Deaths in Iran: 2015-2017
عمومى
General
پژوهشي
Research
<h3><span style="font-family:Tahoma;"><strong>Background</strong>: Given the increasing prevalence of methadone overdose and the growing number of deaths in Iran, the present study was conducted to determine the mortality rate of methadone detected in the cadavers brought to the Forensic Medicine Organization between 2015 and 2017.<br>
<strong>Methods</strong>: This cross-sectional study was performed on 7,486 cases of substance abuse deaths registered in the Forensic Medicine Organization during 2015-2017. In order to investigate the drug abuse, samples collected from the cadavers were initially examined for their drug contents, such as methadone, by standard screening methods and then confirmed by Thin Layer Chromatography (TLC). Using two checklists, the information collected about each cadaver consisted of the identity, autopsy and laboratory data. After data collection, they were entered into the Stata software version 14 MP.<br>
<strong>Results</strong>: The cadavers’ mean age was 36.6±12.6 years. Over the 3-year duration of the study, the standardized mortality rate increased from 35 to 39 cases per million per year. Of these cases, 6066 were randomly assigned to toxicology, 50.1% had used methadone one month before their death. Approximately 75% of the methadone abusers had taken another drug simultaneously, mostly morphine or methamphetamine.<br>
<strong>Conclusion</strong>: Considering the relatively high prevalence of methadone detected post-mortem, monitoring for methadone entry into public market and identifying the death-related factors in the drug abusers are considered as significant measures to improve upon the current alarming situation in the Iranian society.</span><br>
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Methadone, Drug abuse, Addiction, Toxicity, Mortality rates
143
150
http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-786-1&slc_lang=en&sid=1
Jalil
Hasani
جلیل
حسنی
jalil68.hasani@gmail.com
100319475328460013013
100319475328460013013
No
Department of Nursing, Kashmar School of Nursing, Mashhad University of Medical Sciences, Mashhad, Iran.
Davood
Mirtorabi
سید داوود
میرترابی
100319475328460013014
100319475328460013014
No
Forensic Medicine Research Center, Forensic Medicine Organization, Tehran, Iran.
Mohammad Reza
Ghadirzadeh
محمدرضا
قدیرزاده
100319475328460013015
100319475328460013015
No
Forensic Medicine Research Center, Forensic Medicine Organization, Tehran, Iran.
Seyed Amirhossein
Mahdavi
سید امیرحسین
مهدوی
100319475328460013016
100319475328460013016
No
Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.
Saeed
Hashemi Nazari
سید سعید
هاشمی نظری
saedh_1999@yahoo.com
100319475328460013017
100319475328460013017
Yes
Department of Epidemiology, Safety Promotion and Injury Prevention Research Center, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.