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Showing 4 results for Type of Study: case report

Mohammad Moshiri, Seyed Reza Mousavi, Leila Etemad,
Volume 10, Issue 1 (1-2016)
Abstract

Background: The herbicide 2, 4-dichlorophenoxyacetic acid (2, 4-D) can cause moderate to lethal poisoning. Although urine alkalization has been recommended as the main treatment, hemodialysis (HD) may be more effective in severe cases.

Case: On 24th June 2014, a 53- year-old man ingested a high amount of 40% 2, 4-D. He suffered from mouth and epigastric burning sensation, vomiting and nausea. He was treated, in Emam Reza’s Hospital of Mashhad University Of Medical Sciences, Mashhad , Iran,  with maintenance daily fluid infusion plus 10 meq/L NaHCO3. Up to 9 hours after exposure, he became progressively stuporous. He developed diarrhea and hypotension, BP=100/60, unresponsive to volume replacement therapy. He received regular hemodialysis (HD) with bicarbonate for three hours. At the end of HD, his blood pressure rose to 110/70 and the level of consciousness began to improve. Four hours later, he was fully conscious with stable blood pressure (130/80 mmHg).

Conclusion: HD may be an effective, safe and fast method for 2, 4-D high dose intoxication induced coma.


Deepak Jain, Ashima Mittal,
Volume 10, Issue 6 (10-2016)
Abstract

Background: Hair dye poisoning, with main toxic component paraphenylene diamine, is a medical emergency. It is on increasing trend in developing countries due to wide availability and low cost of hair dyes. It carries a high mortality and does not have any specific antidote.

Case Report:  Twenty three years old patient presented with breathelessness along with difficulty in speaking for one hour after consuming hair dye. He developed cervicofacial edema followed by rhabdomyolysis, myoglobinuria and acute kidney injury, classical of hair dye poisoning. Laboratory investigations revealed blood urea of 100 mg/dl and serum creatinine of 3.8 mg/dl. The serum creatinine phosphokinase (CPK) levels were 1230 U/L and urine myoglobin was positive. He was treated conservatively for acute kidney injury and discharged in stable condition.

Conclusion: Early diagnosis and treatment of poisoning due to hair dyes leads to improved prognosis, so widespread awareness is needed about this emerging form of poisoning.


Alireza Ebadollahi-Natanzi, Gholamreza Arab-Rahmatipour ,
Volume 11, Issue 4 (5-2017)
Abstract

Background: Medicinal plants have potential to affect therapeutically procedures. In this study, the therapeutical effects of psyllium on a patient with highly increased level of uric acid, creatinine, and urea have been studied.

Case Report: The case was a 50-yr-old woman affected by diabetes mellitus. Her blood biochemical analyses, showed an increased levels of uric acid (9.70±0.30mg/dL), urea (93.00± 3.60mg/dL) and creatinine (2.30±0.20 mg/dL). She was taken allopurinol (100 mg /daily) followed by consumption of 5 gr/daily from psyllium seeds which continued for two consecutive weeks. Then, the levels of uric acid, urea and creatinine were reached the normal value so that their measured levels were 5.60±0.26; 34.00±1.73 and 1.10±0.10 mg/dL, respectively. Psyllium together with allopurinol could also reduce cholesterol and triglyceride levels in this patient.

Conclusion: We can conclude that psyllium along with allopurinol can synergistically decrease the increased levels of uric acid, creatinine, and urea.


Mohammad Moshiri, Arya Hedjazi, Seyed Mohsen Rezazadeh-Shojaie, Leila Etemad,
Volume 14, Issue 1 (1-2020)
Abstract

Background: Incorrect belief about opioid efficacy is a major cause of acute pediatric poisonings in Iran. We report a rare case of topical opium application that caused death in a 4-year-old child. 
Case: A 4-year old girl was examined with burns over her abdominal area and lower extremities. Her parents had applied opium on burned area to relieve her pain. She was in delirium state and apnea without any evidence of infection. Immediately, she was administered a single dose of Naloxone (2mg). 
Results: While blood oxygen saturation was improving, she aspirated her vomitus into the lungs and became hypotensive and pulseless. Her condition deteriorated and the treatment team’s efforts to resuscitate her failed. On her autopsy, there were no other abnormal findings, but codeine and morphine were detected in the autopsied tissue sample. 
Conclusion: The plausible contributing factors may include: change in morphine pharmacokinetics in the burned skin; the low toxic dose of opium in children due to thin abdominal skin, and high blood perfusion in the burned areas.


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