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Showing 3 results for Rahbar Taromsar

Morteza Rahbar Taromsar, Ali Reza Badsar, Choubineh Mah Manzar, Morteza Fallah Karkan,
Volume 6, Issue 17 (Summer 2012)
Abstract

Background:Naltrexone is a competitive opioid receptor antagonist blocking the euphoric effects of exogenous opioids. When used concomitantly with opioids, naltrexone causes severe withdrawal symptoms.The main aim of the study is to determine the symptomatology and outcome of patients who consumed naltrexone in conjunction with an opioid substance.
Methods:This cross-sectional study was performed on the patients hospitalized with history of naltrexone usage coincided with opioid substances at Razi Hospital, Rasht, Iran. The collected data were demographic information, abuse information, clinical signs and symptoms, laboratory findings, and therapeutic measures taken. Data analysis was performed by descriptive tests using SPSS software version 16.
Results: The mean age of the patients was 33.7±10.2. The majority of the cases were male (95.6%) and urban (96.7%). The main cause of withdrawal symptoms in 91.1% of the patients was inappropriate naltrexone usage.The main poisoning agent in 80% of the cases was consumed naltrexone alone. The route of consumption in 90.1% of the cases was oral and in 9.9% the cases was IV injection. The major clinical features were nausea, vomiting, and agitation.The main therapeutic measures were supportive intravenous fluids (94.8%) and opioid administration in the form of methadone. The mean hospitalization period was 21.8±18 hours.
Conclusion: Severity, clinical course, and outcome of opioid withdrawal by accidental or intentional naltrexone abuse varies greatly among patients and is unpredictable. Common findings upon presentation were gastrointestinal symptoms and agitation and the main therapeutic measures for these patients were support with intravenous fluids and anti-nausea drugs administration as plasil and opioid administration as methadone.
Morteza Rahbar Taromsari , Alireza Badsar, Mohammadreza Aghajankhah , Manochehr Akbar Poor , Nastaran Farhamand Porkar, Morteza Fallah Karkan ,
Volume 6, Issue 19 (Winter 2013)
Abstract

Background: Cardiac manifestations that occur in a majority of patients with organophosphate (OP) poisoning may range from innocuous electrocardiographic manifestations, such as sinus tachycardia, to life-threatening complications, including cardiogenic pulmonary edema and myocardial necrosis. In this study, we evaluated the various electrocardiographic manifestations in patients with OP poisoning.
Methods: This retrospective-descriptive study was performed by reviewing the medical records from all patients poisoned with organophosphate admitted to Razi Educational Hospital, Rasht, Iran, from April 2008 to March 2011. Patients with incomplete records were excluded from the study. Histories of all patients were collected and ECG analysis was conducted including the rate, rhythm, ST-T abnormalities, conduction defects, and measurement of PR and QT intervals by a cardiologist. Descriptive statistical analysis was conducted by SPSS software version18.
 Results: Of the total 100 patients (75 were male) with OP poisoning that referred to the Emergency Ward of Razi Hospital, 63 patients presented ECG abnormalities. The mean age of the patients was 35.78 ± 12.91 years. The causes of poisoning were occupational in 71 patients, suicidal in 26 patients, and accidental in 3 patients. Sinus tachycardia (31%) was the most common ECG abnormality, followed by non-specific ST-T changes (24%). Overall, mortality rate was 5% and all of the deceased patients presented changes in ECG.
Conclusion: OP poisoning is associated with significant ECG abnormalities, especially tachycardia and non-specific ST-T changes.
Morteza Rahbar Taromsari, Alireza Badsar, Keyvan Aminian, Habib Allah Abiar, Morteza Fallah Karkan, Sina Montazeri, Keyvan Abbasi,
Volume 7, Issue 22 (Autumn 2013)
Abstract

Background: Caustics produce one of the most serious complications of poisonings. This research was aimed to study demographical, clinical and endoscopic findings in patients with corrosive injury.
Methods: In a retrospective survey, all records of the patients who had been admitted to Razi and 17th Shahrivar hospital in Rasht city due to the ingestion of caustic agents during 2002-2009 and endoscopy had been performed for them in the first 24 hours after ingestion were studied. The information was analyzed by descriptive method using SPSS 16 software.
Results: Among 258 patients in Razi Hospital, 174 (67.4%) were female with mean age of 29.33 years old. 127 patients (61.1%) had intentional ingestion. 208 patients were finally studied. Among them, 175 patients were hospitalized for 2 days (average 1.73 days). Among 45 patients of 17th Shahrivar hospital, 24 (53.3%) were female. All of them had accidental ingestion. The most frequent site of injury in adults was esophagus (37.2%) and in pediatric population was the mouth (66.6%). Of all pediatric patients, one case had grade IIb endoscopic injury. Among cases who underwent endoscopy (in adults),20.8%, 16.7%, 41.6%, 16.7%,4.2% had grade zero, I, IIa, IIb and III injury, respectively .In all cases, bleaches were the most frequent consumed material.
Conclusion: In both studied groups, female patients were more affected by corrosive agents and in adults, intentional ingestion was approximately 1.5 times more frequent than the accidental cases while all of pediatric patients had accidental poisoning. Most of the lesions had been received only medical treatment without any surgical interventions.

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