Firouzeh Hosseini, Iraj Sedighi, Sadegh Saba, Mozhgan Safari,
Volume 1, Issue 3 (Autumn 2007)
Abstract
Background: Unintentional drug intoxication is still a major cause of mortality and morbidity in young children.
Method & Materials: In order to study changes of epidemiological indices of children intoxication during a 10-year period in Hamadan Province, all cases admitted to Ghaem Hospital from 1995-1999 were recruited, and compared with all cases admitted to the same hospital from 1990-1994.
Results: Mortality rate due to poisoning (4.8% to 0.6%), the time between intoxication and admission to the hospital (12 hours to 5.5 hours) and incidence of poisoning with Diphenoxylate (24.7% to4.4%) had decreased. The patients recieved more supportive care than the past, e.g. gastric washing (23.5% to30.8%), oxygen therapy (11.6% to18.3%), and serum therapy (6.2% to19.9%).
Conclusion: Unfortunately, opioid intoxication (9.4%to13.8%), benzodiazepines intoxication (8.2% to13.8%), improper conditions at home (parental addiction, separation, psychological illnesses, and death and having two or more sibling under 5 years of age) increased. Male gender, seasonal predominance (summer and spring), accidental poisoning and oral route of intoxication were similar in both studies .It is concluded that because opioid and benzodiazepines intoxication in urban children have increased, immediate preventive programs are highly recommended.
Iraj Sedighi, Firozeh Hossein, Mahmood Rezaei, Roshanak Benabbas,
Volume 6, Issue 16 (Spring 2012)
Abstract
ABSTRACT
Background: Acute opium intoxication is one of the most common causes of poisoning in children in Iran. Although most cases are accidental, traditional misuse of opium for symptomatic therapy of various childhood diseases also contributes to high rate of opium intoxication in Iran.
Cases: Here, we report two cases of opium intoxication in infants resulted from transdermal application of opium on burned skin. To our knowledge this is the first case report of intoxication from transdermal misuse of opium.
Conclusion: Health care providers should be aware about signs and symptoms of opium intoxication in children. Opium intoxication should be suspected in each child with history of a recent burn injury that presented with decreased level of consciousness.
