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:: Volume 9, Issue 28 (Spring 2015) ::
IJT 2015, 9(28): 1284-1286 Back to browse issues page
Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning
Ali Banagozar Mohammadi , Hamid Noshad , Ali Ostadi , Ali Reza Ghaffari , Maryam Zaare Nahandi , Ahad Banagozar Mohammadi
MD. Chronic Kidney Diseases Research Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. , hamidnoshad1@yahoo.com
Abstract:   (2526 Views)
Background: Acrylamide (C3H5NO) is a vinyl monomer. This water-soluble crystalline solid is a colorless, odorless agent which is used in scientific laboratories and some industries. Acrylamide has cellular oxidative effects. Acute or chronic poisoning with this agent happens as a result of skin, respiratory, or oral contacts. Clinical manifestations depend on the dose, duration, and frequency of contact. Management of these patients consists of conservative and palliative therapies to reduce the oxidative effects.
Case: The case was a 29-year-old girl with a Master of Sciences degree in genetics who worked in a university research center with previous history of depression. She had ingested 100cc of 30% Acrylamide solution for intentional suicide attempt. The patient was successfully managed using N-acetyl cysteine, vitamin C, and melatonin.
Conclusion: Early diagnosis and appropriate treatment with recommended agents together with supportive therapies can save the life of patients exposed to potentially lethal doses of acrylamide, although intentional or accidental.
Keywords: Acrylamide, Acute Poisoning, Lethal Dose, Treatment.
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Type of Study: Research | Subject: Special
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Banagozar Mohammadi A, Noshad H, Ostadi A, Ghaffari A R, Zaare Nahandi M, Banagozar Mohammadi A. Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning. IJT. 2015; 9 (28) :1284-1286
URL: http://ijt.arakmu.ac.ir/article-1-408-en.html

Volume 9, Issue 28 (Spring 2015) Back to browse issues page
مجله سم شناسی و مسمومیتهای ایران Iranian Journal of Toxicology
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