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Volume 18, Issue 2 (May 2024)
IJT 2024, 18(2): 106-112 |
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Ethics code: YDU/2020/83-1163
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Muhammed D S H, Saygi S. Urinary Bisphenol-A Identification in an Iraqi Population. IJT 2024; 18 (2) :106-112
URL: http://ijt.arakmu.ac.ir/article-1-1290-en.html
URL: http://ijt.arakmu.ac.ir/article-1-1290-en.html
1- Department of Toxicology, Faculty of Pharmacy, Near East University, Nicosia, North Cyprus , dastansalim@yahoo.com
2- Professor, Department of Toxicology, Faculty of Pharmacy, Near East University, Nicosia, North Cyprus
2- Professor, Department of Toxicology, Faculty of Pharmacy, Near East University, Nicosia, North Cyprus
Abstract: (749 Views)
Background: Investigation into environmental chemicals and their impact on human health is a topic of great interest. It is essential to understand the relationship between the quantity of chemical substances involved and the prevalence of particular diseases. Bisphenol-A (BPA) is a disrupting agent to human endocrine health. Human exposure to BPA is on the rise due to the widespread use of this agent, particularly in manufacturing industries. This study aimed to investigate the concentrations of BPA in the Iraqi population.
Methods: This study aimed to determine the amount of BPA in the urine samples of 100 adults residing in the three cities of Diyalah, Kirkuk, and Solaymania in northeastern Iraq. After the subjects’ urine samples were collected, the overall, free, and conjugated BPA contents of the samples were measured using high-performance liquid chromatography and mass spectroscopy (HPLC/MS). The data were adjusted based on the precalculated creatinine levels in the subjects.
Results: Urine samples were collected from 100 individuals residing in three different cities in Iraq, comprising 47 men and 53 women. The concentrations of BPA in all participants’ urine samples ranged from greater than the limit of quantification to 80.24 µg/g creatinine, with a calculated geometric mean of 4.17 µg/g creatinine.
Conclusion: The findings of this preliminary study indicated that the Iraqi population’s level of BPA exposure falls within an acceptable range. To provide a more accurate estimate of BPA exposure nationwide, further investigations on larger sample sizes are required across a wider range of age and gender distributions.
Methods: This study aimed to determine the amount of BPA in the urine samples of 100 adults residing in the three cities of Diyalah, Kirkuk, and Solaymania in northeastern Iraq. After the subjects’ urine samples were collected, the overall, free, and conjugated BPA contents of the samples were measured using high-performance liquid chromatography and mass spectroscopy (HPLC/MS). The data were adjusted based on the precalculated creatinine levels in the subjects.
Results: Urine samples were collected from 100 individuals residing in three different cities in Iraq, comprising 47 men and 53 women. The concentrations of BPA in all participants’ urine samples ranged from greater than the limit of quantification to 80.24 µg/g creatinine, with a calculated geometric mean of 4.17 µg/g creatinine.
Conclusion: The findings of this preliminary study indicated that the Iraqi population’s level of BPA exposure falls within an acceptable range. To provide a more accurate estimate of BPA exposure nationwide, further investigations on larger sample sizes are required across a wider range of age and gender distributions.
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Arak University of Medical Sciences in collaboration with the Iranian Society of Toxicology
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