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:: Volume 7, Number 23 (Winter 2014) ::
IJT 2014, 7(23): 962-966 Back to browse issues page
Methicillin Resistant Staphylococcus Aureus in Ventilator Associated ‎Pneumonia in Toxicological Intensive Care Unit
Alireza Salimi, Sepideh ‎ Kamalbeik‎, Arezou Mahdavinejad, ‎ Shahram‎ Sabeti, ‎ Haleh‎ Talaie *
Toxicological Research Center, Department of Clinical Toxicology, Loghman- Hakim Hospital, Shahid ‎Beheshti University of Medical Sciences, Tehran, Iran.‎ , talaie@sbmu.ac.ir
Abstract:   (8208 Views)
Background: Methicillin resistant Staphylococus Aureus (MRSA) is a cause of ‎nosocomial infections at intensive care unit (ICU), which imposes a high mortality and ‎morbidity on the health care systems.‎ The objective of this study was to evaluate the role of MRSA in patients with clinically ‎suspected ventilator associated pneumonia (VAP) in toxicological ICU admitted ‎patients.
Methods:
This cross-sectional study was performed over a period of six months from ‎August 2009 to February 2010. A total of 84 patients with clinically suspected VAP were ‎selected from all 381 ICU admitted patients under mechanical ventilation for more than ‎‎48 hours. MRSA Screen Agar was used to detect resistance in Staph aureus ‎specimens. MRSA was determined as the main outcome.‎
Results: MRSA was the cause in 54% of Staph aureus infected VAPs. Although ‎MRSA infection was not significantly associated with age, gender, cause of poisoning, ‎chronic disease, paraclinical findings, length of hospital stay, and antibiotic prescription ‎‎(P>0.05 for all comparisons), it was reported higher in those who expired than those ‎who survived (66.7% vs. 31.9%, P<0.012)‎.
Conclusion: In the main referral toxicological ICU in Tehran, in more than 1 of 3 ‎clinically suspected VAP cases, MRSA was seen which was associated with the poorer ‎outcome, higher inpatient mortality.‎
Keywords: Intensive Care Unit, Methicillin Resistance, Pneumonia, Staphylococus ‎Aureus, Ventilator.‎
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Type of Study: Research | Subject: Special
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Salimi A, Kamalbeik‎ S ‎, Mahdavinejad A, Sabeti ‎ S, Talaie ‎ H. Methicillin Resistant Staphylococcus Aureus in Ventilator Associated ‎Pneumonia in Toxicological Intensive Care Unit. IJT. 2014; 7 (23) :962-966
URL: http://ijt.arakmu.ac.ir/article-1-279-en.html
Volume 7, Number 23 (Winter 2014) Back to browse issues page
مجله سم شناسی و مسمومیتهای ایران Iranian Journal of Toxicology
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