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Volume 7, Issue 23 (Winter 2014)                   IJT 2014, 7(23): 973-976 | Back to browse issues page

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Nnoli M, Lebgbosi N L, Chukwuonye ‎ I I, Nwabuko C O. Toxicological Investigation of Acute Carbon Monoxide Poisoning in ‎Four Occupants of a Fuming Sport Utility Vehicle ‎. IJT. 2014; 7 (23) :973-976
URL: http://ijt.arakmu.ac.ir/article-1-280-en.html
1- Department of Pathology and Forensic Medicine, University of Calabar, Cross-River State, Nigeria.‎ , mnnoli@yahoo.com
2- Department of Pharmacology/Toxicology, Wilberforce Island, Bayelsa State, Nigeria. ‎
3- Department of Internal Medicine/Hematology, Federal Medical Center Umuahia, Abia State, Nigeria.‎
4- Department of Hematology, Federal Medical Center, Umuahia, Abia State, Nigeria.‎
Abstract:   (6039 Views)
Background: This toxicological investigation involves a report on the death of four ‎occupants of a sport utility vehicle on one of the major busy Federal roads of Nigeria ‎where they were held for up to three hours in a traffic jam while the car was steaming.‎
Methods: Autopsy was executed using the standard procedure and toxicological ‎analysis was done using simple spectrophotometric method to establish the level of ‎carboxyhaemoglobin (HbCO) in peripheral blood in the four occupants.
Results: The autopsy report indicated generalized cyanosis, sub-conjuctival ‎hemorrhages, marked laryngo-trachea edema with severe hyperemia with frothy fluid ‎discharges characteristic of carbon monoxide poisoning. Toxicological report of the level ‎of HbCO in part per million (ppm) in the peripheral blood of the four occupants was A= ‎‎650 ppm B= 500 ppm C= 480 ppm, and D= 495 ppm against the maximum permissible ‎level of 50 ppm.‎
The sudden death of the four occupants was due to excessive inhalation ‎of the carbon monoxide gas from the exhaust fumes leaking into the cabin of the car. ‎The poor road network, numerous potholes, and traffic jam in most of roads in Nigeria ‎could have exacerbated a leaky exhaust of the smoky second hand SUV car leading to ‎the acute carbon monoxide poisoning. ‎
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Type of Study: Research | Subject: Special

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