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Volume 3, Issue 3 (Autumn 2010)                   IJT 2010, 3(3): 311-316 | Back to browse issues page

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Behnoush B, Bazmi E, Akhgari M, Hashemi Nazari S S, Sardari Iravani F. Evaluation of Ethanol and N-propanol in Victims. IJT. 2010; 3 (3) :311-316
URL: http://ijt.arakmu.ac.ir/article-1-54-en.html
1- Department of Forensic Medicine, Tehran University of Medical Sciences, Tehran, Iran
2- Laboratory of Forensic Toxicology, Scientific and Educational Research Center of Legal Medicine Organization of Tehran, Tehran, Iran
3- Department of Epidemiology and Biostatistics School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Abstract:   (13800 Views)
Background: Blood alcohol concentration is a major factor in forensic analysis in criminal and civil litigation. Along with ethanol, other volatile compounds such as n-propanol are produced as products of putrefaction. The aim of this study is the evaluation of ethanol and n-propanol in postmortem blood.
Methods: A case-control study was done on 300 blood samples obtained from cadavers that were referred to Legal Medicine Organization (LMO) of Tehran, Iran, over a year (2009-2010). Blood ethanol and n-propanol concentrations were analyzed in duplicate by HSGC. Data on cadavers were taken from the information sheets and were analyzed by SPSS software.
Results: In this study, mean n-propanol level in blood was 8.311 mg/dl in putrefied and 1.58 mg/dl in non-putrefied victims. Interval times between death and autopsy in putrefied and non-putrefied victims were 3.5 and 1.25 days. Results show that n-propanol concentrations increase 1.23 mg/dl/day after death. In 99% of putrefied victims, ethanol level was more than 10 mg/dl. There was a high correlation between ethanol and n-propanol concentrations. By increasing 1mg/dl of n-propanol concentration, ethanol levels increased 2.5 and 1.4 mg/dl in putrefied and non-putrefied victims, respectively.
Conclusion: N-propanol produced in putrefied victims with ethanol. Production of ethanol increased by rising n-propanol levels. Therefore, we might use n-propanol as a putrefaction factor in postmortem blood to distinguish endogenous and exogenous ethanol production.
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Type of Study: Research | Subject: General

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